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HOME > 教育・研究 > 研究業績 > 2017年研究業績

研究業績

2017年研究業績

Genome-Wide Association Study of Clinically Defined Gout Identifies Multiple Risk Loci and Its Association with Clinical Subtypes

Matsuo H1), Yamamoto K(Kurume Univ.), Nakaoka H2), Nakayama A1), Sakiyama M1), Chiba T1), Takahashi A3), Nakamura T3), Nakashima H1), Takada Y1), Danjoh I3), Shimizu S1), Abe J1), Kawamura Y1), Terashige S1), Ogata H1), Tatsukawa S1), Yin G4), Okada R4), Morita E4), Naito M4), Tokumasu A5), Onoue H1), Iwaya K1), Ito T(Self-Defense Forces Central Hosp.), Takada T5), Inoue K5), Kato Y(Kagawa Univ.), Nakamura N3), Sakurai Y1) Suzuki H5)(5Tokyo Univ. of Pharmacy and Life Sciences), Kanai Y(osaka Univ.), Hosoya T, Hamajima N4)(4Nagoya Univ.), Inoue I2)(2National Institute of Genetics), Kubo M3)(3RIKEN), Ichida K, Ooyama H5)(5Ryougoku East Gate Clinic), Shimizu T(Midorigaoka Hosp.), Shinomiya N1)(1National Defense Medical College),.
Ann Rheum Dis. 2016; 75(4): 652-9

GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes

Nakayama A1), Nakaoka H(National Institute of Genetics), Yamamoto K2), Sakiyama M1), Shaukat A3), Toyoda Y4), Okada Y5)(Tokyo Medical and Dental Univ.)(Osaka Univ.), Kamatani Y5) Nakamura T1), Takada T4), Inoue K6)(6Tokyo Univ of phamacy and Sciences), Yasujima T7), Yuasa H7)(7Nagoya City Univ.), Shirahama Y2), Nakashima H1), Shimizu S1), Higashino T1), Kawamura Y1), Ogata H1), Kawaguchi M1), Ohkawa Y(Kyushu Univ.), Danjoh I(Tohoku Univ.), Tokumasu A8), Ooyama K8), Ito T(Self-Defense Forces Central Hosp.) , Kondo T9) Wakai K9)(9Nagoya Univ.), Stiburkova B10)(Charles Univ. in Prague and General Univ. Hosp.), Pavelka K10)(10Institute of Rheumatology), Stamp LK3), Dalbeth N(Univ of Auckland); Eurogout Consortium, Sakurai Y1), Suzuki H4)(4The Univ. of Tokyo Hosp.), Hosoyamada M11), Fujimori S11)(11Teikyo Univ.), Yokoo T, Hosoya T, Inoue I2)(2Kurume Univ.), Takahashi A5)(Omics Research Center, National Cerebral and Cardiovascular Center), Kubo M5)(5RIKEN), Ooyama H8)(8Ryougoku East Gate Clinic), Shimizu T(Midorigaoka Hosp.)( Kyoto Industrial Health Association) , Ichida K, Shinomiya N1), Merriman TR3)(3Univ.of Otago), Matsuo H1)(1National Defense Medical College).
Ann Rheum Dis. 2016; 76(2): 869-77

An angiotensin II type 1 receptor binding molecule has a critical role in hypertension in a chronic kidney disease model

Kobayashi R1), Wakui H1), Azushima K1), Uneda K1), Haku S1), Ohki K1), Haruhara K, Kinguchi S1), Matsuda M1), Ohsawa M1), Toya Y1), Nishiyama A(Kagawa Univ.), Yamashita A1), Tanabe K2), Maeshima Y2)(2Okayama Univ.), Umemura S1), Tamura K1)(1Yokohama City Univ.).
Kidney Int. 2017; 91(5): 1115-25

Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2

Matsuo H1), Tsunoda T2), Ooyama K3), Sakiyama M1), Sogo T2), Takada T4), Nakashima A, Nakayama A1), Kawaguchi M1), Higashino T1), Wakai K(Nagoya Univ.), Ooyama H3)(3Ryougoku East Gate Clinic), Hokari R1), Suzuki H4)(4The Univ. of Tokyo Hosp.), Ichida K, Inui A2)(2Saiseikai Yokohamashi Tobu Hosp.), Fujimori S(Teikyo Univ.), Shinomiya N1)(1National Defense Medical College)
Sci Rep. 2016; 6: 31003

High-density Association Mapping and Interaction Analysis of PLA2R1 and HLA Regions with Idiopathic Membranous Nephropathy in Japanese

Thiri M1), Honda K1), Kashiwase K(Japanese Red Cross Kanto-Koshinetsu Block Blood Center), Mabuchi A1), Suzuki H2), Watanabe K2), Nakayama M, Watanabe T2)(2Fukushima Medical Univ.), Doi K1), Tokunaga K1), Noiri E1)(1The Univ. of Tokyo).
Sci Rep. 2016; 6: 38189

Adipocyte-Specific Enhancement of Angiotensin II Type 1 Receptor-Associated Protein Ameliorates Diet-Induced Visceral Obesity and Insulin Resistance

Azushima K1)(Duke-NUS Medical School), Ohki K1), Wakui H1), Uneda K1), Haku S1), Kobayashi R1), Haruhara K , Kinguchi S1), Matsuda M1), Maeda A1), Toya Y1), Yamashita A1), Umemura S1), Tamura K1)(1Yokohama City Univ.).
J Am Heart Assoc. 2017; 6(3): e004488

Glomerular Density and Volume in Renal Biopsy Specimens of Children with Proteinuria Relative to Preterm Birth and Gestational Age

Koike K, Ikezumi Y1), Tsuboi N, Kanzaki G, Haruhara K, Okabayashi Y, Sasaki T, Ogura M, Saitoh A1)(1Niigata Univ.), Yokoo T.
Clin J Am Soc Nephrol. 2017; 12(4): 585-90

Identification of Febuxostat as a New Strong ABCG2 Inhibitor: Potential Applications and Risks in Clinical Situations

Miyata H1), Takada T1), Toyoda Y1), Matsuo H(National Defense Medical College), Ichida K, Suzuki H1)(1The Univ. of Tokyo Hosp.).
Front Pharmacol. 2016; 7: 518

A phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of etelcalcetide (ONO-5163/AMG 416), a novel intravenous calcimimetic, for secondary hyperparathyroidism in Japanese haemodialysis patients.

Fukagawa M(Tokai univ.), Yokoyama K2, Shigematsu T(Wakayama Medical Univ), Akiba T(Sekikawa Hosp.), Fujii A1), Kuramoto T1)(1Clinical Development Planning), Odani M(Ono Pharmaceutical Co. Ltd), Akizawa T(Showa Univ.); ONO-5163 Study Group.
Nephrol Dial Transplant. 2017; https://doi.org/10.1093/ndt/gfw408

ATRAP Expression in Brown Adipose Tissue Does Not Influence the Development of Diet-Induced Metabolic Disorders in Mice

Ohki K1), Wakui H1), Azushima K1)(Duke-NUS Medical School), Uneda K1), Haku S1), Kobayashi R1), Haruhara K, Kinguchi S1), Matsuda M1), Ohsawa M1), Maeda A1), Minegishi S1), Ishigami T1), Toya Y1), Yamashita A1), Umemura S1)(Yokohama Rosai Hosp.), Tamura K1)(1Yokohama City Univ.).
Int J Mol Sci. 2017; 18(3): E676

Correction: Adipose Tissue-Derived Mesenchymal Stem Cells in Long-Term Dialysis Patients Display Downregulation of PCAF Expression and Poor Angiogenesis Activation

Yamanaka S, Yokote S, Yamada A, Katsuoka Y, Izuhara L, Shimada Y, Omura N, Okano HJ, Ohki T, Yokoo T.
PLoS One. 2016; 11(6): e0157282

Diabetic phenotype of transgenic pigs introduced by dominant-negative mutant hepatocyte nuclear factor 1α

Umeyama K1), Nakajima M(Nihon Univ.), Yokoo T, Nagaya M1), Nagashima H1)(1Meiji Univ.).
J Diabetes Complications. 2017; 31(5): 796-803

A Novel Compound Heterozygous Mutation in the SLC22A12 (URAT1) Gene in a Japanese Patient Associated with Renal Hypouricemia

Fujita K(Tokyo Univ. of Pharmacy and Life Science), Ichida K
Clin Chim Acta. 2016; 463: 119-21

Preventive Strategies for Vascular Calcification in Patients with Chronic Kidney Disease.

Shigematsu T1), Sonou T1), Ohya M1), Yokoyama K, Yoshida H, Yokoo T, Okuda K1), Masumoto A..R1), Isashita Y1), Iseki K1), Kunimoto S1), Yamano Y1)(1Wakayama Medical Univ.).
Contriutions to Nephrology. 2017; Vol.189: 169-77

A new peritoneal dialysis fluid for Japanese patients: a randomized non-inferiority clinical trial of safety and efficacy

Nakayama M, Kawaguchi Y, Akiba T(Sekikawa Hosp.)(Tokyo Women's Medical Univ.), Kim M(Kaikou Clinic)(Kaiko-Kai Clinic), Naito H(Naito Medical Research Laboratory)(Sano Ikawadani Hosp.), Hara S(Hara Press Center Clinic)(Toranomon Hosp.), Maeba T(Asao Kidney Clinic)(St. Marianna Univ.), Yorioka N(Hiroshima Kidney Organization)(Hiroshima Univ.), Sloand JA(Baxter Healthcare Corporation), Marshall MR(Baxter Healthcare (Asia) Pte Ltd)(Univ. of Auckland).
Clin Exp Nephrol. 2016; Epub 2016 Oct. 25

Possible prevention of uremic nausea by vitamin D receptor activators in non-dialysis patients with stage 5 chronic kidney disease

Ikeda M, Ueda Y, Maruyama Y, Yokoyama K, Yokoo T, Joki N(Toho Univ.), Ando R(Musashino Red Cross Hosp.), Shinoda T(Kawakita General Hosp.), Inaguma D(Nagoya Daini Red Cross Hosp.), Yamaka T(Kanagawa Institute of Technology), Komatsu Y(St. Luke's International Hosp.), Koiwa F(Showa Univ.), Sakaguchi T1), Negi S1), Shigematsu T1)(1Wakayama Medical Univ.)
Clin Exp Nephrol. 2016; Epub 2016 Nov. 14

Recurrence and graft loss after renal transplantation in adults with IgA vasculitis

Kawabe M, Yamamoto I, Komatsuzaki Y, Yamakawa T, Katsumata H, Katsuma A, Mafune A, Nakada Y, Kobayashi A, Tanno Y, Ohkido I, Tsuboi N, Yokoyama K, Horita S1), Okumi M1), Ishida H1), Yamamoto H, Yokoo T, Tanabe K1)(1Tokyo Women's Medical Univ.); Japan Academic Consortium of Kidney
Clin Exp Nephrol. 2016; Epub 2016 Sep. 27

Usefulness of combination therapy with Daclatasvir plus Asunaprevir in chronic hepatitis C patients with chronic kidney disease

Morisawa N, Koshima Y1), Satoh JI1)(1Saitama Red Cross Hosp.), Maruyama Y, Kuriyama S, Yokoo T, Amemiya M.
Clin Exp Nephrol. 2016; Epub 2016 Oct. 22

Embryonic kidney function in a chronic renal failure model in rodents

Fujimoto E1), Yamanaka S, Kurihara S, Tajiri S, Izuhara L, Katsuoka Y1), Yokote S, Matsumoto K, Kobayashi E(Keio Univ.), Okano HJ, Chikaraishi T1)(1St. Marianna Univ.), Yokoo T.
Clin Exp Nephrol. 2016; Epub 2016 Sep. 30

Functional Analysis of Novel Allelic Variants in URAT1 and GLUT9 Causing Renal Hypouricemia Type 1 and 2

Mancikova A1), Krylov V1), Hurba O1), Sebesta I1), Nakamura M(Tokyo Univ. of Pharmacy and Life Science), Ichida K, Stiburkova B1)(1Charles Univ.)
Clin Exp Nephrol. 2016; 20(4): 578-84

Impact of hemoglobin levels on renal and non-renal clinical outcomes differs by chronic kidney disease stages: the Gonryo study

Yamamoto T1), Miyazaki M1), Nakayama M, Yamada G1), Matsushima M, Sato M2), Sato T2), Taguma Y1)2)(2Japan Community Health Care Organization Sendai Hosp.), Sato H1), Ito S1)(1Tohoku Univ.).
Clin Exp Nephrol. 2016; 20(4): 595-602

Hypermethylation of the CaSR and VDR genes in the parathyroid glands in chronic kidney disease rats with high-phosphate diet

Uchiyama T, Tatsumi N, Kamejima S, Waku T(Doshisha univ.), Ohkido I, Yokoyama K, Yokoo T, Okabe M.
Human Cell. 2016; 29(4): 155-61

The prognostic values of caveolin-1 immunoreactivity in peritubular capillaries in patients with kidney transplantation

Nakada Y, Yamamoto I, Horita S1), Kobayashi A, Mafune A, Katsumata H, Yamakawa T, Katsuma A, Kawabe M, Tanno Y, Ohkido I, Tsuboi N, Yamamoto H, Okumi M1), Ishida H1), Yokoo T, Tanabe K1)(1Tokyo Women's Medical Univ.); Japan Academic Consortium of Kidney Transplantation (JACK).
Clin Transplant. 2016; 30(11): 1417-24

Risk factors for encapsulating peritoneal sclerosis: analysis of a 36-year experience in a University Hospital

Nakao M, Yamamoto I, Maruyama Y, Morishita M, Nakashima A, Matsuo N, Tanno Y, Ohkido I, Ikeda M, Yamamoto H, Yokoyama K, Yokoo T.
Nephrology (Carlton). 2016; Epub 2016 Aug. 24

Circadian blood pressure abnormalities in patients with primary nephrotic syndrome

Haruhara K, Tsuboi N, Koike K, Kanzaki G, Okabayashi Y, Sasaki T, Fukui A, Miyazaki Y, Kawamura T, Ogura M, Yokoo T.
Clin Exp Hypertens. 2017; 39(2): 155-9

Comparison of direct renin inhibitor and angiotensin II receptor blocker on clinic and ambulatory blood pressure profiles in hypertension with chronic kidney disease

Uneda K1), Tamura K1), Wakui H1), Azushima K1), Haku S1), Kobayashi R1), Ohki K1), Haruhara K, Kinguchi S1), Ohsawa M1), Fujikawa T1), Umemura S1)(1Yokohama City Univ.).
Clin Exp Hypertens. 2016; 38(8): 738-43

Effect of single-pill irbesartan/amlodipine combination-based therapy on clinic and home blood pressure profiles in hypertension with chronic kidney diseases

Kobayashi R1), Tamura K1), Wakui H1), Ohsawa M1), Azushima K1), Haku S1), Uneda K1), Ohki K1), Haruhara K, Kinguchi S1), Umemura S1)(1Yokohama City Univ.).
Clin Exp Hypertens. 2016; 38(8): 744-50

The differences in acid-base status and the calcium parathyroid axis between peritoneal dialysis and hemodialysis

Morishita M, Matsuo N, Maruyama Y, Nakao M, Yamamoto I, Tanno Y, Ohkido I, Ikeda M, Yokoyama K, Yokoo T.
Clin Nephrol. 2016; 86(2): 55-61

Expression of a Human NPT1/SLC17A1 Missense Variant Which Increases Urate Export

Sakiyama M1), Matsuo H1), Nagamori S2), Ling W2), Kawamura Y1), Nakayama A1), Higashino T1), Chiba T1), Ichida K, Kanai Y2)(2Osaka Univ.), Shinomiya N1)(1National Defense Medical College.)
Nucleosides Nucleotides Nucleic Acids. 2016; 35(10-12): 536-42

Clinicopathologic Impact of Early Medullary Ray Injury in Patients Following Kidney Transplantation

Niikura T, Kobayashi A, Kawabe M, Katsuma A, Yamakawa T, Katsumata H, Mafune A, Nakada Y, Yamamoto I, Tanno Y, Ohkido I, Okumi M1), Ishida H1), Yamamoto H, Yokoo T, Tanabe K1)(1Tokyo Women's Medical Univ.); Japan Academic Consortium of Kidney Transplantation (JACK).
Transplant Proc. 2017; 49(1): 78-83

Fluctuation in Serum Sodium Levels Related to Ipragliflozin Administration in a Patient with Diabetic Nephropathy and Sequela of Traumatic Brain Injury

Okonogi H, Harada M1), Sato H1), Tokoro K1), Nakayama I1)(1Kanagawa Rehabilitation Hosp.), Tsuboi N, Miyazaki Y, Kawamura T, Ogura M, Yokoo T.
Intern Med. 2016; 55(14): 1887-91

Overlap of Post-obstructive Diuresis and Unmasked Diabetes Insipidus in a Case of IgG4-related Retroperitoneal Fibrosis and Tuberoinfundibular Hypophysitis: A Case Report and Review of the Literature

Sasaki Yatabe M1)2), Watanabe K1), Hayashi Y1), Yatabe J2), Morimoto S2), Ichihara A2)(2Tokyo Women's Medical Univ.), Nakayama M, Watanabe T1)(1Fukushima Medical Univ.)
Intern Med. 2017; 56(1): 47-53

Dialyzer-related Thrombocytopenia due to a Polysulfone Membrane

Kobari E1), Terawaki H, Takahashi Y1), Kusano Y1), Sakurai K1), Matsunaga K1), Fukushima N1), Suzuki S1), Tanaka K1), Hayashi Y1), Watanabe T1)(1Fukushima Medical Univ.), Nakayama M .
Intern Med. 2016; 55(8): 965-8

Helicobacter cinaedi bacteremia with cellulitis in a living-donor kidney transplant recipient identified by matrix-assisted laser desorption ionization time-of-flight mass spectrometry: a case report

Katsuma A, Yamamoto I, Tsuchiya Y, Kawabe M, Yamakawa T, Katsumata H, Mafune A, Nakada Y, Kobayashi A, Koike K, Shimizu A, Tanno Y, Ohkido I, Tsuboi N, Hori S, Yamamoto H, Yokoo T.
BMC Res Notes. 2017; 10(1): 87

Salmonella enterica ssp.arizonae菌血症に腸腰筋膿瘍および胸椎椎間板炎を合併した78歳女性の1例

天野 方一, 小林 政司, 保科 斉生, 岡田 秀雄, 長谷川 俊男, 川口 良人, 横尾 隆
日本内科学会雑誌 2017; 106(1): 84-9

ステロイドおよびシクロスポリンが有用であったTAFRO症候群の1例

森澤 紀彦, 佐藤 博之1), 松山 桃子1), 林 直美, 安達 章子1), 佐藤 順一1)(1さいたま赤十字病院), 横尾 隆, 雨宮 守正
日本内科学会雑誌 2016; 105(12): 2432-9

急性大腿動脈血栓塞栓症により右下肢切断に至ったステロイド依存性ネフローゼ症候群の1例 [A case of right femoral artery thromboembolism in steroid-dependent nephrotic syndrome]

福永 昇平, 松本 啓, 丹野 有道, 須藤 航(沖縄県立八重山病院), 上原 元太1), 宮里 均1)(1沖縄県立中部病院), 坪井 伸夫, 小倉 誠, 横尾 隆
日本腎臓学会誌 2016; 58(4): 604-9

腎移植後intact PTHと予後との関連

山川 貴史, 川口 武彦1), 西村 元伸1), 首村 守俊1), 今澤 俊之1), 横尾 隆, 青山 博道1), 大月 和宣1), 丸山 通広1), 圷 尚武1), 長谷川 正行1), 西郷 健一1)(1構千葉東病院)
日本臨床腎移植学会雑誌 2016; 4(2): 208-11

生体腎移植後に常染色体劣性Alport症候群が疑われた1例

川邊 万佑子, 山本 泉, 小松嵜 陽, 山川 貴史, 勝俣 陽貴, 勝馬 愛, 中田 泰之, 小林 賛光, 清水 昭博, 丸山 之雄, 丹野 有道, 小池 祐介, 三木 淳, 山田 裕紀, 大城戸 一郎, 坪井 伸夫, 山本 裕康, 横尾 隆
日本臨床腎移植学会雑誌 2016; 4(2): 257-61

高血圧を合併した2型糖尿病患者におけるDPP-4阻害薬の降圧効果

栗山 哲, 中野 知子1), 田邉 智子1), 山嵜 眞由美1), 真家 健一1), 真島 香代子1)(1東京国税局診療所), 森澤 紀彦, 菅野 直希, 横尾 隆
血圧 2016; 23(12): 885-9

腎代替医療の基礎研究の現状

山本 泉, 横尾 隆
Medical Science Digest 2017; 43(5): 13-5

高血圧およびCKD発症の初期リスクとしての高尿酸血症 8年間の大規模コホート研究から

西尾 信一郎, 栗山 哲, 細谷 龍男, 横尾 隆
痛風と核酸代謝 2016; 40(1): 33-46

小腸使用膀胱拡大術を実施後19年目に多発骨折がみられた代謝性アシドーシスの1例

曾田 瑛子, 中田 泰之, 山本 泉, 丹野 有道, 大城戸 一郎, 横山 啓太郎, 横尾 隆
臨床体液 2016; 43: 3-8

症例による透析患者の画像診断 末期腎不全に対して左前腕内シャント造設後に左鎖骨下動脈盗血症候群と診断された1例

嵯峨崎 誠, 菅野 直希, 山中 修一郎, 中田 泰之, 内山 威人, 山本 泉, 松尾 七重, 丸山 之雄, 大城戸 一郎, 横尾 隆
臨床透析 2017; 33(1): 108-12


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